The availability of numerous vaccines and the rapid advancement of medical technologies today allow us to fight human diseases much more effectively than in the past. This remarkable progress is due to a better understanding of immunity, which is the ability of the host organism to protect itself. The Vaccines, Inflammation and Immunomonitoring Platform aims to understand how immunity and inflammation can influence therapeutic responses and disease progression. By focusing on the immune and inflammatory microenvironment, the platform prioritizes the identification of predictive immunological biomarkers to support Personalized Medicine.
MAIN INFRASTRUCTURES AND METHODOLOGIES AVAILABLE
The Vaccines, Inflammation and Immunomonitoring Platform supports an integrated approach to the use of advanced immunomonitoring technologies as a strategic tool to guide therapeutic decisions, improve prognostic accuracy, and optimize clinical intervention strategies.
It leverages advanced infrastructures and cutting-edge technologies, provides high-quality immunomonitoring services, analyzes the effects of vaccines and therapies, and integrates immunological and clinical data to accelerate innovation and advance Personalized Medicine in Italy.
The Platform brings together multidisciplinary expertise spanning immunology, infectious and immune-mediated diseases, oncology, vaccinology, immune-based therapies, cell and molecular biology, biochemistry, pharmacology, gene therapy, epidemiology, imaging, nanotechnologies, and veterinary medicine.
It provides comprehensive support on national and international regulatory frameworks, legal and quality aspects, GMP manufacturing, technology transfer, and interactions with regulatory authorities such as EMA and FDA.
The Platform supports the design and development of vaccines and therapeutic strategies for infectious and non-infectious diseases, from early research to translational application.
APPLICATIONS
- Evaluation of the immunological efficacy of vaccines and immunotherapies
- Analysis of immune responses to gene and cell therapies
- Immune profiling associated with drug administration
- Identification and validation of predictive immunological biomarkers
- Patient stratification in clinical trials (distinguishing responders from non-responders)
- Sharing and dissemination of knowledge about the immune system
- Support for translational research and therapeutic innovation
